Switching off MDSCs by targeting REL
نویسندگان
چکیده
منابع مشابه
Improving cancer immunotherapy by targeting the STATe of MDSCs
Cancer immunotherapy is a promising therapeutic avenue; however, in practice its efficacy is hampered by an immunosuppressive tumor microenvironment that consists of suppressive cell types like myeloid-derived suppressor cells (MDSCs). Eradication or reprogramming of MDSCs could therefore enhance clinical responses to immunotherapy. Here, we review clinically available drugs that target MDSCs, ...
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ژورنال
عنوان ژورنال: Nature Reviews Cancer
سال: 2020
ISSN: 1474-175X,1474-1768
DOI: 10.1038/s41568-020-0277-7